The influence of ABO blood groups on sensitization of potential kidney transplant recipients

Authors

  • Ahmed Hassan Department of Nephrology, Zaggazig University
  • Mohamed Sherif Department of Microbiology & Immunology, Al-Azhar University
  • Rasha Khalil Department of Microbiology & Immunology, Ain Shams University
  • Medhat Zaki Department of Microbiology & Immunology, Al-Azhar University

DOI:

https://doi.org/10.21804/2-1-859

Abstract

In this study 50 chronic renal failure patients were tested for blood ABO groups and for the presence of lymphocytotoxic antibodies against a panel of 20 donor lymphocytes (of known HLA types) using microcytotoxicity assay. The influence of other factors affecting sensitization, such as number of blood transfusions, pregnancies and previous graft rejections were analyzed too. The results showed that 41.2 % of blood group 0 patients, 61.1 % of group A I, 90% of group B, and 80% of group A IB are sensitized (PRA> 10%). These results pointed to higher incidence of sensitization in patients with blood groups B and A IB as compared to groups A I and 0.Our data suggest an impact of the ABO system on the sensitization phenomenon.

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Published

2016-08-07

How to Cite

Hassan, Ahmed, Mohamed Sherif, Rasha Khalil, and Medhat Zaki. 2016. “The Influence of ABO Blood Groups on Sensitization of Potential Kidney Transplant Recipients”. African Journal of Nephrology 2 (1):30-33. https://doi.org/10.21804/2-1-859.

Issue

Vol. 2 No. 1 (1998)

Section

Original articles

License

Copyright (c) 2016 Ahmed Hassan, Mohamed Sherif, Rasha Khalil, Medhat Zaki

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.